That’s some visible progress in only 50 minutes! And a room with good bones, so to say. Spacious, no odd angles or impractical nooks and crannies, practical furniture and layout. You can see it was a nice, well-thought out craft space originally.
Personally, I’m a multi-crafting, although I suppose heavily leaning towards fiber / textile. Some years I’m more into garment sewing, other years I do more cross stitch, etc. My space is limited so I make sure my stash is limited (which means, I don’t buy ‘for stash’, I buy what I need for specific projects). That doesn’t mean I have no stash at all, there’s the inherited / gifted stuff, leftovers/scraps, UFOs and WIPs, projects that don’t work out, and obviously the tools for each craft. But I don’t get rid of things because it’s not my craft that year.
I have gotten rid of some things because I felt I was never going to do them again. If any supply doesn’t spark joy for you, it’s time to let it go. I think that’s a similar approach to your question - if you are getting back into, say, crochet, right now, would you really use the amigurimi supplies? Or did these end up in a drawer somewhere because you never actually enjoyed amigurimi in the first place? That’s a sign to get rid of them.
From a different perspective, are there supplies that you own that someone else could really use? For example a charity or school? Say you’ve got a die cutting machine that you might want to use again years from now, but has been gathering dust for a while, and you know a preschool teacher who would really get a lot of use out of it, you could let it go and pass it on as an act of kindness.
Last one, is there anything that you haven’t touched in a long time, but is worth some money? In that case it might be worth considering listing it for sale. If you are ever going to get into that craft again, you can always buy it again, but maybe that moment never comes. In the mean time, you’ve got more space and more money.